While some wouldn't make an immediate connection between mysteries and comedies, the two genres can and have combined their respective appeal. The daring blend of genres gave way to films that many still hold near and dear to their hearts today. From box office juggernauts to cherished cult classics, comedies with a compelling mystery weave hilarious lines and jaw-dropping twists into their plots. The crème de la crème highlights the strengths of both genres and the creativity of the cast and crew.